Molecular and Cellular Basis of Neurodegenerative Disease

The Molecular and Cellular Basis of Neurodegenerative Diseases: Fundamental Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. The most common form of senile dementia is Alzheimer’s disease (AD), which is characterized by the extracellular deposition of amyloid β-peptide (Aβ) plaques and the intracellular formation of neurofibrillary tangles (NFTs) in the cerebral cortex. Tau abnormalities are commonly observed in many neurodegenerative diseases including AD, Parkinson’s disease, and Pick’s disease

  • Track 1-1 Molecular Bases of Neurological Diseases
  • Track 2-2 Cognitive and Emotional Deficits
  • Track 3-3 Anatomical and Functional Basis of Dementia and Neurodegeneration
  • Track 4-4 Mitochondria and Protein Quality Control Dysfunction
  • Track 5-5 RNA and DNA Regulatory Proteins
  • Track 6-6 Bridging Biology to Therapeutics
  • Track 7-7 Prion and Prion-Like Contributions to Neurodegeneration
  • Track 8-8 Inducible Pluripotent Stem Cells

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