Nanotechnology for Neurodegenerative Disorders

The most common issues in the diagnosis and treatment of different disorders are the efficacy, cellular uptake and specific transport of drugs and/or imaging agents to target organs, tissues and cells are. The major problem in the case of neurodegenerative diseases is that the brain targeting remains an unsolved challenge in pharmacology, due to the presence of the blood-brain barrier, a tightly packed layer of endothelial cells that prevents unwanted substances to enter the brain. The physico-chemical features of the engineered nanomaterials, objects with dimensions of 1-100 nm, are providing interesting biomedical tools potentially able to solve these problems. The nanomaterials offer the possibility of multi-functionalization, allowing to confer them different features at the same time, including the ability to cross the blood-brain barrier. Many investigations have shown that these nanomaterials are suitable for therapy and diagnostic imaging of the most common neurodegenerative disorders, as well as for neuroprotection and neuronal tissue regeneration

  • Track 1-1 Micellar Nanocarriers
  • Track 2-2 Superparamagnetic Iron Oxide Nanoparticles
  • Track 3-3 Nanotheranostics
  • Track 4-4 Enhanced Magnetic Resonance Imaging
  • Track 5-5 Drug Delivery Systems
  • Track 6-6 Multimodal Imaging Approaches

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